A syringe (1) for carpules (2) comprises a body (3) having a cavity (31) for receiving a fluid- containing carpule (2), the body (3) having a first through opening (32), facing the cavity (31) and adapted to be engaged by a needle (4), and a second through opening (33), facing the cavity (31) and configured to allow insertion of said carpule (2) into the cavity (31). The syringe (1) comprises a plunger (6) configured to evacuate the fluid from the carpule (2). The syringe comprises a cover (5), attached to the body (3) and adapted to be switched between a closed position, in which the cover (5) engages the second opening (33), and an open position, in which the second opening (33) is free, The cover (5) has a hole (51), and the plunger (6) is configured to be slidingly inserted in the hole (51), when the cover (5) is in the closed position.