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カルシム含有化合物および糖アルコールを含む微粒状物
专利权人:
ニコメド ファーマ エイエス
发明人:
マティエセン,ヤコブ,ニールセン,カルステン マルティニ,オルセン,ペダー モー,ベルテルセン,ポール,エゴン
申请号:
JP2007513680
公开号:
JP5112860B2
申请日:
2005.05.24
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
The present invention relates to a particulate material and a solid dosage form notably tablets comprising a regularly shaped calcium-containing compound such as a calcium salt as a therapeutically and/or prophylactically active substance and a pharmaceutically acceptable sugar alcohol such as, e.g., sorbitol and/or isomalt that has a micro structure as evidenced by SEM. The invention also relates to a process for the preparation of the particulate material and solid dosage form. The process involves agglomeration of the calcium-containing compound and the pharmaceutically acceptable sugar alcohol by means of roller compaction. The particulate material obtained by roller compaction is suitable for use in the further processing of the particulate material into e.g. tablets such as chewing tablets.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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