NOUVEAUX DERIVES DE TETRAHYDROPYRAZOLO[3,4-B]AZEPINE ET LEUR UTILISATION EN TANT QUE MODULATEURS ALLOSTERIQUES DE RECEPTEURS METABOTROPIQUES DU GLUTAMATE
JONES, PHILIP,TANG, LAM,BOLEA, CHRISTELLE,CELANIRE, SYLVAIN,LIVERTON, NIGEL J.
申请号：
CA2807318
公开号：
CA2807318A1
申请日:
2011.07.11
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The present invention relates to novel compounds of Formula (I), wherein M, A and Y are defined as in Formula (I)； invention compounds are modulators of metabotropic glutamate receptors - subtype 4 ("mGluR4") which are useful for the treatment or prevention of central nervous system disorders as well as other disorders modulated by mGluR4 receptors. The invention is also directed to pharmaceutical compositions and the use of such compounds in the manufacture of medicaments, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR4 is involved.
