WANG, LUNGHU,CHEN, YUNG, FA,HENSCHKE, JULIAN, PAUL
申请号:
EP08727257
公开号:
EP2146719A4
申请日:
2008.04.02
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
A novel process for the preparation of N-methyl-N-(2-[4-hydroxyphenyl]ethyl)-5-hydroxy-4-methoxy benzene carboxamide, which is useful as an intermediate in the synthesis of (−)-galantamine, comprises the reaction of a 5-hydroxy-4-methoxy benzoic acid derivative with N-methyl-N-(2-[4-hydroxyphenyl]ethyl) amine.