Abraham Nudelman,Ada Rephaeli,Irit Gil-Ad,Abraham Weizman,Mazal Shaul,Efrat Halbfinger
申请号:
US13825369
公开号:
US08916610B2
申请日:
2011.09.22
申请国别(地区):
US
年份:
2014
代理人:
摘要:
An acid addition salt of a nortriptyline-GABA conjugate, a novel crystalline form of a fumaric acid addition salt of a nortriptyline-GABA conjugate, and processes of preparing the forgoing are disclosed. Uses of the above-indicated forms of a nortriptyline-GABA conjugate in the treatment of CNS disorders, and in the treatment of pain in particular, are also disclosed. Further disclosed in a large-scale process of preparing a nortriptyline-GABA conjugate.