A novel pharmaceutical compound having bactericidal action against tubercle bacilli and sythesis thereof

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专利权人:

发明人:

Dr GHATE Manjunath,BAROT Kuldipsinh

申请号：

IN1903/MUM/2013

公开号：

IN2013MU01903A

申请日:

2013.05.30

申请国别(地区):

IN

年份:

2015

代理人:

摘要：

A Novel Benzamidazole Derivatives and synthesis thereof whereby novel benzimidazole derivatives are (R)-2-(4"-methoxyphenyl)-3-(3",5"-diflorophenyl)-1,2,3,5- tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol (KPB 13) and (R)-2-(4"-methoxyphenyl)-3-(2"-hydroxy,5"-methoxyphenyl)-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol (KPB 15) having potent antitubercular activity. The said KPB 13 and KPB 15 have the structure shown below which are active against M. tuberculosis including drug-resistant mycobacteria and some non-tuberculosis mycobacteria.

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中国工程科技知识中心

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