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MULTI-FUNCTIONALIZED POLYSACCHARIDE COMPOUNDS AND USE THEREOF FOR TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR
专利权人:
Nanomedsyn
发明人:
MORERE, Alain,DA SILVA, Afitz,BOUFFARD, Elise,EL CHEIKH, Khaled,DURAND, Jean-Olivier,MAYNADIER, Marie,BASILE, Ilaria
申请号:
EP16787487
公开号:
EP3350192A1
申请日:
2016.09.15
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The subject matter of the present invention is a compound characterized in that it has the general formula (I): in which P1, X, n, A, L and L1 are as defined in Claim 1. The present invention also relates to a process for preparing said compounds (I) and to the use thereof for targeting the cation-independent mannose 6-phosphate receptor (CI-M6PR). The subject matter of the invention is also a conjugate of formula (III): in which P1, X, n, A, L and L1 are as defined in Claim 6, and the use thereof: - in a method for therapeutic treatment of the human or animal body, in particular chosen from enzyme replacement therapy, photodynamic therapy or cancer treatment, and/or - in a method of diagnosis, in particular of diseases or of ailments associated with an increase or with a decrease in CI-M6PR expression.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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