A prepolymer for biomedical materials has the following formula:X1 represents aliphatic compounds or aromatic compounds, X3 represents alkene-containing compounds, X2 represents siloxane compounds having the following formula. In one embodiment of the present invention, n is between l and 20, m is between 10 and 20, and y is between 1 and 7.本發明之生醫材料之預聚物,具有下列化學式:其中X1係脂肪族化合物或芳香族化合物,X3係含烯官能基化合物,X2係具有下列化學式之矽氧烷化合物。在本發明之一實施例中,n係介於1至20之間,m係介於10至20之間,y係介於1至7之間。