GSK-3阻害剤

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专利权人:

ノスシラ、ソシエダッド、アノニマ

发明人:

アナ、マルティネス、ヒル,イザベル、ドロンソロ、ディアス,メルセデス、アロンソ、カスコン,ヘマ、パニソ、デル、プリエゴ,アナ、フエルテス、ウエルタ,マリア、ホセ、ペレス、プエルト,ミゲル、メディナ、パディーリャ

申请号：

JP2007506716

公开号：

JP4995076B2

申请日:

2005.04.04

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

Provided arc thiadiazolidinc compounds of formula I wherein R1 is an organic group having at least 8 atoms selected from C or O, which is not linked directly to the N through a -C(O)- and comprising at least an aromatic ring, and their pharmaceutical compositions. These compounds are selective GSK-3 inhibitors and have improved bioavailability. They are useful for the treatment of GSK-3 mediated diseases, among others Alzheimers disease, type II diabetes, depression and brain injury.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/