PHARMACEUTICAL COMPOSITION FOR PREVENTION, TREATMENT OR DELAY OF ALZHEIMER'S DISEASE OR DEMENTIA CONTAINING G PROTEIN-COUPLED RECEPTOR 19 AGENT AS ACTIVE INGREDIENT
Seung Yong SEONG,Jung Ah CHO,Tae Joo KIM,Youn Hee KIM
申请号:
US15516317
公开号:
US20180104261A1
申请日:
2016.01.15
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a pharmaceutical composition for preventing, treating or delaying an Alzheimer's disease (AD) or dementia including a G protein-coupled receptor19 (GPCR19) agonist or its pharmaceutically acceptable salt as an active ingredient and a food composition for preventing, treating or delaying an Alzheimer's disease or dementia. The GPCR19 agonist according to the present invention has an effect of improving cognitive and behavioral disorders without harming the health of objects when administrated to the objects and has an effect of preventing the Alzheimer's disease or dementia or delaying or treating the progression of the disease in the objects with the disease by suppressing apoptosis of the brain tissue, enhancing immunity, and reducing formation of an amyloid β (Aβ) plague.