Martin Hunter,Annika Enejder,Thomas Scecina,Michael Feld,Wei-Chuan Shih
申请号:
US11412418
公开号:
US08355767B2
申请日:
2006.04.27
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to the use of Raman spectroscopy for quantitative, non-invasive transcutaneous measurement of blood analytes, such as glucose. Raman spectroscopy is used to measure glucose transcutaneously, in patients whose blood glucose levels were monitored. Raman spectra were collected transcutaneously along with glucose reference values provided by standard capillary blood analysis. A partial least squares calibration was created from the data from each subject and validated using leave-one-out cross validation.