PROBLEM TO BE SOLVED: To provide a compound having potent cysLT1/cysLT2 receptor antagonistic activity, keeping the activity for a long time even by oral administration and having potent oral activity useful as an oral agent for prevention and/or treatment of respiratory diseases.SOLUTION: The compound is expressed by general formula (I) (in the formula, R1 is carboxymethyl or 3-carboxypropyl R2 is a hydrogen atom or 1C-4C alkyl R3 is [1-(carboxymethyl)cyclopropyl]methyl or 3-carboxypropyl R4 is a hydrogen atom or halogen atom and ring 1 is expressed by formula (in the formula R5 is 1C-4C alkyl or a halogen atom m is 0 or integer of 1-5 when m is &ge2, the R5 groups may be the same or different and the arrow shows bonding with butyloxy group)).COPYRIGHT: (C)2010,JPO&INPIT【課題】強力にcysLT1/cysLT2受容体を拮抗し、経口投与においてもその効果が長時間持続し、例えば、呼吸器疾患の予防および/または治療のための経口剤として有用である強力な経口活性を有す化合物の提供。【解決手段】一般式(I)で示される化合物。【選択図】なし
