Treating overactive bladder syndrome, using a dosage form comprising a immediate-release component and a extended-release component, each comprising acetaminophen and ibuprofen, each in an amount of 5 mg to 2000 mg in each component. The extended-release component may comprise an insoluble matrix, a polymer controlling release by dissolution controlled release, a water soluble or water-swellable matrix-forming polymer or a enteric coating.
