The present invention relates to the benzene derivatives that the glucopyranosyl of general formula I replaces, and wherein R1 to R6 is defined as in the description with R7a, R7b, R7c base, including tautomer, its stereoisomer, its mixture and its salt； It is related to the pharmaceutical composition comprising the compounds of this invention； It is related to the purposes of the compounds of this invention treatment metabolic disorder； And it is related to the preparation method and intermediate of the compounds of this invention.本發明涉及通式I的吡喃葡萄糖基取代的苯衍生物，其中R1至R6與R7a、R7b、R7c基如說明書中所定義，包括互變異構體、其立體異構體、其混合物及其鹽；涉及包含本發明化合物的藥物組合物；涉及本發明化合物治療代謝病症的用途；以及涉及本發明化合物的製備方法和中間體。
