Zhao, Weiying,Ni, Quan,Ruble, Stephen,Hamann, Jason
申请号：
AU2012261486
公开号：
AU2012261486A1
申请日:
2012.12.04
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2012261486A120130110.pdf#####C: \NRPortbl\DCC\LJR\4786348_1.DOC - 4/12/12 ABSTRACT A method for titrating an intensity of an open loop vagal stimulation therapy 5 (VST) to a therapeutically-effective dose for a cardiovascular disease, wherein the VST includes vagal stimulation (VS) delivered to a vagus nerve using an implantable medical device, the method comprising setting the intensity of the open loop VST after implantation of the device, wherein setting the intensity includes setting the intensity to avoid significant bradycardia and performing 10 one or more follow-up therapy titration procedures, wherein performing the one or more follow-up therapy titration procedures includes adjusting the intensity of the open loop VST to provide the therapeutically-effective dose for the cardiovascular disease without causing VS-induced slowing of heart rate during VS. 47
