University of Southern California;University of California;University Of California At Santa Barbara
发明人:
Humayun, Mark,Ahuja, Ashish,Tai, Yu-Chong.,Hinton, David,Grubbs, Robert,Clegg, Dennis,Jhonson, Lincoln Vallance,Hikita, Sherry T.
申请号：
AU2011279250
公开号：
AU2011279250A1
申请日:
2011.07.12
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
Substrates for cell delivery to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide seeded cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue. A substrate for cellular therapy to treat diseased or damaged ocular tissue, comprising a non-porous polymer having an apical and basal surface, wherein the substrate is configured to support a population of cells suitable for the treatment of diseased or damaged ocular tissue, and wherein, upon implantation into a subject, the substrate supports the population of cells for a period of time sufficient to treat the diseased or damaged ocular tissue.
