Tim D. Cabelka,Akshay Bellare,Ka Chun A. Chan,Tina P. Dasbach,Kacee B. Ender,Karl V. Jacob,Robert E. Scheid, JR.
申请号:
US14316879
公开号:
US20140308356A1
申请日:
2014.06.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A granular material which hasa mean particle diameter of 150 to 800 micrometers; andan unsettled bulk density of 0.1 to 0.35 g/cm3 and/or a compactibility which results in a compact with a tensile strength of at least 1.7 MPa when the granular material is subjected to a compaction pressure of 266 MPa; andwherein the main component of the granular material is a cellulose derivative or an alkylene oxide homo- or copolymer or a blend thereofis useful for preparing dosage forms with a controlled release profile.