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FORMES CRISTALLINES DE L'ACIDE (S)-2-AMINO-3-(4-(2-AMINO-6-((R)-1- (4-CHLORO-2-(3-METHYL-1H-PYRAZOL-1-YL)PHENYL)-2,2,2-TRIFLUOROETHOXY)- PYRIMIDIN-4-YL)PHENYL)PROPANOIQUE
专利权人:
LEXICON PHARMACEUTICALS; INC.
发明人:
LI, QUN,HU, WEIFENG,YANG, XIAOGEN,ZHAO, JIANGQIONG,ZHAO, MATTHEW MANGZHU
申请号：
CA2816963
公开号：
CA2816963A1
申请日:
2011.11.03
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
Crystalline forms of (S) - 2 -amino- 3 - (4 - (2 -amino- 6 - ( (R) - 1 - (4 - chloro- 2 - (3 -methyl - lH-pyrazol - 1 -yl) phenyl) - 2, 2, 2 - trifluoroethoxy) pyrimidin - 4 -yl) phenyl) propanoic acid and salts thereof are disclosed. Pharmaceutical dosage forms and methods of their use are also disclosed.
来源网站：
中国工程科技知识中心
来源网址：
http://www.ckcest.cn/home/
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CRYSTALLINE FORMS OF ( S ) - 2 - AMINO - 3 - (4 - ( 2 - AMINO - 6 - ( (R) - 1 - (4 - CH LORO-2- (3-METHYL- 1H- PYRAZOL- 1 -YL) PHENYL) - 2, 2, 2 - TRIFLUOROETHOXY) PYRIMIDIN- 4 - YL) PHENYL) PROPANOIC ACID
CRYSTALLINE FORMS OF ( S ) - 2 - AMINO - 3 - (4 - ( 2 - AMINO - 6 - ( (R) - 1 - (4 - CH LORO-2- (3 -METHYL- 1H- PYRAZOL- 1 -YL) PHENYL) - 2, 2, 2 - TRIFLUOROETHOXY) PYRIMIDIN- 4 - YL) PHENYL) PROPANOIC ACID
CRYSTALLINE FORMS OF (S)-2-AMINO-3-(4-(2-AMINO-6-((R)-1-(4-CHLORO-2-(3-METHYL-1H-PYRAZOL-1-YL)PHENYL)-2,2,2-TRIFLUOROETHOXY)PYRIMIDIN-4-YL)PHENYL)PROPANOIC ACID
Solid forms of (S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoic acid
Solid forms of (S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoic acid
