UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;THEUNITED STATES OF AMERICA; AS REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICE;THEUNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICE
发明人:
GREIG, Nigel, H.,LUO, Weiming,TWEEDIE, David,VARGESSON, Neil,BEEDIE, Shaunna,FIGG, William, Douglas
申请号:
USUS2016/054430
公开号:
WO2017/059062A1
申请日:
2016.09.29
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Thalidomide analogs and methods of using the thalidomide analogs are disclosed. Some embodiments of the disclosed compounds exhibit anti- angiogenic and/or anti-inflammatory activity. Certain embodiments of the disclosed compounds are non-teratogenic.L'invention concerne des analogues de la thalidomide et des procédés d'utilisation de ces analogues. Dans certains modes de réalisation, les composés de la présente invention présentent une activité anti-angiogénique et/ou anti-inflammatoire. Dans d'autres modes de réalisation, les composés de l'invention sont non-tératogènes.