GREENSPAN, DAVID C.,WEST, JON K.,LEE, SEAN,MEYERS, JAMES L.,DIAMOND, MASON
申请号：
CA2343223
公开号：
CA2343223C
申请日:
1999.09.10
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Compositions and methods for treating wounds to significantly reduce thehealing time, reduce the incidence of scar formation, improve the success ofskin grafts, reduce the inflammatory response and providing anti-bacterialtreatments to a patient in need thereof, that include small non-interlinkedparticles of bioactive glass or highly porous bioactive glass, are disclosed.Anti-bacterial solutions derived from bioactive glass, and methods ofpreparation and use thereof, are also disclosed. The compositions include non-interlinked particles of bioactive glass, alone or in combination with anti-bacterial agents and/or anti-inflammatory agents. The compositions can includean appropriate carrier for topical administration. Anti-bacterial propertiescan be imparted to implanted materials, such as prosthetic implants, sutures,stents, screws, plates, tubes, and the like, by incorporating small bioactiveglass particles or porous bioactive glass into or onto the implantedmaterials. Anti-bacterial properties can also be imparted to devices used forin vitro and ex vivo cell culture by incorporating non-interlinked particlesof bioactive glass into the devices. Anti-bacterial compositions derived fromaqueous extracts of bioactive glass are also disclosed. These compositions canbe used, for example, in food preparation, solutions used for cell culture,and buffer solutions, such as i.v. solutions.
