SHIN, HYUN KYOO,신현규,JUNG, JU YOUNG,정주영,HA, HYE KYUNG,하혜경,SEO, CHANG SEOB,서창섭,KIM, YOUNG JUNG,김영중
申请号:
KR1020120125452
公开号:
KR1020130115072A
申请日:
2012.11.07
申请国别(地区):
KR
年份:
2013
代理人:
摘要:
PURPOSE: A pharmaceutical composition and a health food containing a natural product extract for preventing or treating acute renal failure are provided to effectively prevent or treat acute renal failure and to suppress side effects caused from an anticancer agent such as cisplatin. CONSTITUTION: A pharmaceutical composition for preventing or treating acute renal failure contains a Trichosanthis semen extract or a fraction thereof as an active ingredient. The extract is prepared using water, C1-C4 alcohols, or a mixture thereof. The extract is prepared by ultrasonic wave extraction, room temperature extraction, hot water extraction, enfleurage extraction, reflux condensation extraction, or steam extraction. The fraction is a hexane fraction, an ethyl acetate fraction, a butanol fraction, or a water fraction. Acute renal failure is caused by an anticancer agent. A health food for preventing or treating acute renal failure contains the extract or the fraction as an active ingredient. [Reference numerals] (AA) Trichosanthes kirilowii (mg/kg)본 발명은 급성신부전의 예방 또는 치료에 효과적인 천연물 추출물로서, 과루인 추출물 또는 이의 분획물을 유효성분으로 함유하는 급성신부전의 예방 또는 치료용 약학적 조성물 및 개선용 건강기능식품 조성물에 관한 것이다.