The present invention provides conjugates of peptide derivatives of themammalian peptide hormones angiotensinogen, angiotensin I and angiotensin II,presented in a repetitive scaffold by coupling the peptide derivatives to acarrier, particularly a virus-like particle (VLP). The invention also providesmethods of producing such conjugates, and immunotherapeutic uses of theresulting immunogen conjugates for the therapy and prophylaxis of conditionsassociated with the reninactivated angiotensin system.
