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IMMUNITY INDUCTION PRODUCT
专利权人:
ТОРЭЙ ИНДАСТРИЗ; ИНК. (JP)
发明人:
КУРИХАРА Акира (JP),ОКАНО Фумиеси (JP)
申请号:
RU2013156368/10
公开号:
RU2013156368A
申请日:
2012.05.18
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. An immune inducing agent comprising, as active ingredient (s), at least one polypeptide having immunity induction activity selected from polypeptides (a) to (c) below and / or a recombinant vector (s) s) containing (e) polynucleotide (s) encoding (e) said at least one polypeptide, where said (e) recombinant (s) vector (s) is capable of expressing said polypeptide (s) in vivo: (a) a polypeptide consisting of at least 7 consecutive amino acids in any of the amino acid sequences the rest of SEQ ID NO: 4, 2, 8, 10 and 12 from the list of sequences; (b) a polypeptide whose sequence is at least 85% identical to the polypeptide specified in (a) and consisting of at least 7 amino acids; and (c) a polypeptide containing said polypeptide (a) or (b) as part of its sequence. The immunity inducing agent according to claim 1, characterized in that said polypeptide having immunity inducing activity is a polypeptide having the amino acid sequence of SEQ ID NO: 4, 2, 8, 10 or 12 from the list of sequences. An immune inducing agent according to claim 1 or 2, which is an agent for treating antigen presenting cells. An immunity inducing agent according to claim 1 or 2, which is a therapeutic and / or prophylactic agent against malignant neoplasm (s). The immunity inducing agent according to claim 4, characterized in that said malignant neoplasm (s) is (are) malignant neoplasm (s) expressing KATNAL1.6. The tool that induces immunity, according to claim 5, excellent1. Средство, индуцирующее иммунитет, содержащее в качестве активного(ых) ингредиента(ов) по меньшей мере один полипептид, обладающий активностью индукции иммунитета, выбранный из полипептидов (а)-(с) ниже, и/или рекомбинантный(ые) вектор(ы), содержащий(е) полинуклеотид(ы), кодирующий(е) указанный по меньшей мере один полипептид, где указанный(е) рекомбинантный(е) вектор(ы) способен(ны) экспрессировать указанный(ые) полипептид(ы) in vivo:(a) полипептида, состоящего не менее чем из 7 последовательных аминокислот в любой из ам
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