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Use of HLA genetic status to assess or select treatment of celiac disease
专利权人:
ImmusanT; Inc.
发明人:
Anderson, Robert P.
申请号:
AU2015323979
公开号:
AU2015323979A1
申请日:
2015.09.29
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
Provided herein are methods of adjusting or selecting a gluten peptide therapy based on the human leukocyte antigen (HLA) genotype, in particular HLA-DQ2.5 homozygosity, of a subject having or suspected of having Celiac disease. Also provided herein are methods of identifying (e.g., diagnosing) a subject, such as a subject having or suspected of having Celiac disease and/or assessing the efficacy of treatment of Celiac disease, e.g. by determining responsiveness to a therapeutic gluten peptide composition or cytokine response, and kits relating thereto.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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