JEAN-JACQUES CADIEUX,SULTAN CHOWDHURY,JIANMIN FU,RAJENDER KAMBOJ,TOM HSIEH,QI JIA,SHIFENG LIU,JIANYU SUN
申请号:
BRPI0719857
公开号:
BRPI0719857A2
申请日:
2007.10.12
申请国别(地区):
BR
年份:
2014
代理人:
摘要:
This invention is directed to methods of using spiro-oxindole compounds of formula (I): wherein j, k, m, Q, X, R1, R2a, R2b, R2c, R2d and R3 are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, N-oxide, solvate or prodrug thereof, for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.