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Substituted naphthyridine and quinoline compounds as mao inhibitors
专利权人:
DART NEUROSCIENCE (CAYMAN) LTD
发明人:
KAPLAN ALAN,BASINGER JILLIAN,FREESTONE GRAEME,GUPTA VARSHA,MAK CHI-CHING,PRATT BENJAMIN,SANTORA VINCENT,SENGUPTA DIPANJAN,VALDEZ LINO
申请号:
NZ71159814
公开号:
NZ711598A
申请日:
2014.03.05
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
The invention provides a chemical entity of Formula (I), wherein R1, R2, R3, Y, and n have any of the values described herein and compositions comprising such chemical entities methods of making them and and their use in a wide range of methods, including metabolic and reaction kinetic studies, detection and imaging techniques, and radioactive treatments and therapies, including inhibiting MAO and MAO-B selectively, enhancing neuronal plasticity, treating neurological disorders, providing neuroprotection, treating a cognitive or motor impairment associated with a CNS disorder, enhancing the efficiency of cognitive and motor training, providing neurorecovery and neurorehabilitation, enhancing the efficiency of non- human animal training protocols, and treating treating peripheral disorders (including obesity, diabetes, and cardiometabolic disorders) and their associated co-morbidities.
来源网站:
中国工程科技知识中心
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