Childrens Medical Center Corporation;Children's Medical Center Corporation
发明人:
Benny-Ratsaby, Ofra,Folkman, Judah
申请号：
AU2008268262
公开号：
AU2008268262C1
申请日:
2008.06.26
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
Described herein are MetAP-2 inhibitors and compositions and formulations thereof, and more particularly compositions and formulations of MetAP-2 inhibitors wherein the MetAP-2 inhibitor is associated with a block copolymer comprising a hydrophilic polymer moiety and a hydrophobic polymer moiety. The present invention also relates to compositions and formulations comprising MetAP-2 inhibitors for oral administration or administration via routes such as topical or ocular administration. The present invention also provides methods to treat conditions associated with or related to the over-expression or over-activity of MetAP-2 by administering the compositions and formulations comprising MetAP-2 inhibitors as disclosed herein.
