A system and method suitable for use during surgery to analyze images at a site within a patient, including obtaining at least a first, reference image of the site, or a corresponding contralateral site, the first image including at least a first anatomical region or a corresponding anatomical region. At least a second, intra-operative results image of the site is obtained. At least one stationary base with at least two base points is selected to serve as a reference for both images during analysis including at least one of scaling, calculations, and image comparisons.