Ram A. Vishwakarma,Sandip B. Bharate,Shashi Bhushan,Dilip M. Mondhe,Shreyans K. Jain,Samdarshi Meena,Santosh K. Guru,Anup S. Pathania,Suresh Kumar,Akanksha Behl,Mubashir J. Mintoo,Sonali S. Bharate,Pr
申请号：
US14784489
公开号：
US09932327B2
申请日:
2014.04.16
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to the rohitukine (5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-4H-chromen-4-ones) analogs of formula A and pharmaceutically acceptable salts thereof. In addition, the invention relates to pharmaceutically acceptable compositions comprising at least one such compound, and methods of using the compounds for treating or preventing various proliferative disorders such as melanoma, leukemia, breast cancer and prostate cancer etc. [insert Formula A here] wherein, n=0 or 1, when n=1, the dotted line indicates the double bond.
