Jürgen Hausmann;Christine Meisinger-Henschel;Mark Suter
发明人:
Jürgen Hausmann,Christine Meisinger-Henschel,Mark Suter
申请号:
US13575773
公开号:
US08859257B2
申请日:
2011.01.28
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides modified vaccinia virus (VACV) genomes as well as vectors, especially viral vectors comprising the same. The present invention further provides modified vaccinia viruses. The present invention further provides methods for determining the effect of mutations in VACV with regard to competence for replication in certain cell types. The present invention further provides methods of preparing modified vaccinia viruses.