Przemyslaw Krawczyk,Jacob A. Aten,Roland Kanaar,Jeroen Essers
申请号：
US13144079
公开号：
US20120022026A1
申请日:
2010.01.13
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to a method of treating or preventing hyperproliferative disease in a body tissue of a subject, comprising the steps of administering to a subject in need thereof a therapeutically effective amount of an agent that induces double strand breaks in the DNA of the hyperproliferative cells of said body tissue and subjecting the hyperproliferative cells of said body tissue prior to, simultaneously with or subsequent to step a) to hyperthermia to thereby induce in said cells the degradation, inhibition and/or inactivation of BRCA2.
