The present invention provides epitope peptides derived from KOC1 with cytotoxic T cell inducing ability. The present invention also provides a polynucleotide encoding the peptide, an antigen presenting cell presenting the peptide, and a method for inducing cytotoxic T cells targeting the peptide, and the antigen presenting cell or the CTL. The present invention further includes compositions and pharmaceutical compositions using these as effective ingredients. The present invention further provides the use of the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells of the present invention, or the pharmaceutical composition of the present invention to treat and/or prevent cancer, and/or prognosis after surgery Method of hair. In addition, a method for inducing an immune response to cancer is provided.本發明提供具有細胞傷害性T細胞誘導能力之來自KOC1的抗原決定位胜肽。本發明並提供編碼為該胜肽之多核苷酸、呈現該胜肽之抗原呈現細胞及誘導以該胜肽為標靶之細胞傷害性T細胞、及該抗原呈現細胞或該CTL之方法。本發明更包含以該等作為有效成分之組合物及藥學組合物。本發明更提供使用本發明之胜肽、多核苷酸、抗原呈現細胞、細胞傷害性T細胞、或本發明之藥學組合物來治療及/或預防癌，及/或預發術後之癌再發之方法。又，提供誘導對於癌之免疫應答之方法。
