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FINGOLIMOD POLYMORPHS AND THEIR PROCESSES
专利权人:
发明人:
申请号:
EP11842990.1
公开号:
EP2646409A1
申请日:
2011.08.29
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention provides crystalline polymorphic forms of Fingolimod HCl (I) and processes for preparation thereof. The application provides processes for preparation of crystalline polymorphic forms-&alpha, &bgr and &mu substantially free from process related impurities. The crystalline polymorphic forms of Fingolimod HCl (I) obtained by the processes according to the present invention having an XRDP pattern as per FIGS. 1, 3 and 5, which are useful as active pharmaceutical ingredient in pharmaceutical compositions for the treatment or prevention of autoimmune related disorder including multiple sclerosis.
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