The inventive technology describes to a novel surgical device having a high-speed rotating hollow cutting needle capable of longitudinally cutting, sampling, removing and/or coring targeted tissue pathologies as well as the efficient collection and/or disposal of said tissue pathologies. In particular, the inventive technology may be suitable for application on lesions near the skin, and/or pathologies internal to the body, and perhaps even especially for procedures performed in conjunction with image guidance, particularly active X-ray, computerized tomography (CT), magnetic resonance imaging (MRI), and/or ultrasound scans, where the presence of a large electro-magnetic field may impose significant constraints on the design and operation of mechanical mechanisms. Additionally, the inventive technology encompasses a system of device assisted targeted delivery of a variety of therapeutic treatments to specific tissue pathologies, through, for example, adaptable therapeutic introducers coordinated with a rotating hollow cutting needle.