Andreas Richard Meijer,Mikkel Jacob Thaning,Paritosh Jayant Dhawale,Salvatore Desena,Paul Alexander Jones,Deirdre Cassidy,Concetta Valeria Gringeri
申请号：
US15768831
公开号：
US20180303960A1
申请日:
2016.11.30
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to in vivo imaging and in particular to magnetic resonance imaging (MRI). Provided by the present invention is a pharmaceutical formulation suitable for use in an MRI procedure and which offers advantages over known such formulations. A particular dose of the pharmaceutical formulation of the invention is also envisioned as well as the use of said dose in a method of in vivo imaging. This present invention provides for simultaneous administration of a liver specific agent and a second MR contrast agent that is capable of better/further enhancing the dynamic vascular phase in a patient. The method of the invention has the advantage of simplicity and patient comfort, compared to sequential injections. Furthermore, the method of the invention provides the advantage that it can enable a lower cumulative dose of contrast agents.
