THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY; PHILADELPHIA
发明人:
ERTL, HILDEGUND C. J.,WILSON, JAMES M.
申请号:
HU0400297
公开号:
HU228327B1
申请日:
2002.05.13
申请国别(地区):
HU
年份:
2013
代理人:
摘要:
A method of inducing a CD8+ T-cell response against a selected molecule by delivering the molecule via a recombinant simian adenovirus is provided. Also provided are methods of inducing interferon-alpha and interferon-beta by delivering a recombinant simian adenovirus to a subject. The methods of the invention are particularly well suited for prophylaxis and treatment of infections with human immunodeficiency virus and human papilloma virus, among others, and cancer therapy.