PROBLEM TO BE SOLVED: To provide a cosmetic composition for application comprising a component that maintains the moisture retention of skin.SOLUTION: A cosmetic composition for application comprises a component that maintains the moisture retention of skin. The cosmetic composition for application comprises a conditioned medium of a dental pulp stem cell, and gel for stabilizing the conditioned medium. The gel comprises a polymer compound that maintains the moisture retention of skin.SELECTED DRAWING: Figure 7COPYRIGHT: (C)2016,JPO&INPIT【課題】肌の保湿性を保つ成分を含む塗布用化粧品組成物を提供する。【解決手段】本発明の塗布用化粧品組成物は、肌の保湿性を保つ成分を含む。塗布用化粧品組成物は、歯髄幹細胞の培養上清と、該培養上清を安定化させるためのジェルと、を含む。ジェルは、肌の保湿性を保つ高分子化合物を含む。【選択図】図7