VERWENDUNG VON MICRORNAS ODER GENEN ALS MARKER ZUR IDENTIFIZIERUNG, DIAGNOSE UND THERAPIE EINZELNER FORMEN NICHT-ISCHÄMISCHER KARDIOMYOPATHIEN ODER SPEICHERERKRANKUNGEN DES HERZENS
IKDT INSTITUT KARDIALE DIAGNOSTIK UND THERAPIE GMBH
发明人:
KÜHL, UWE,SCHULTHEISS, HEINZ-PETER,LASSNER, DIRK,ROHDE, MARIA
申请号:
EP13712154.7
公开号:
EP2820131A2
申请日:
2013.02.26
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The invention relates to the use of certain microRNAs and/or genes, both individually and as a combination of several, in the form of profiles as markers for identifying individual forms of non-ischemic cardiomyopathies or storage diseases of the heart, and to their use in diagnostic systems for identifying individual forms of non-ischemic cardiomyopathies or storage diseases of the heart, which includes at least some of these microRNAs and/or genes. The invention furthermore relates to a method for identifying and differentiating between individual forms of non-ischemic cardiomyopathies or storage diseases of the heart using at least individual ones of these microRNAs and/or genes. The invention further relates to a medicament which contains at least one nucleic acid which includes a sequence which is identical or complementary to the sequence of one of these microRNAs.