A handheld diabetes management device includes a bG measurement engine, a data store, a display, and a testing module. The bG measurement engine selectively measures bG levels in blood samples. The data store includes data for executing a plurality of structured tests, each of the structured tests calling for execution of one or more of: a first procedure including prompting the patient to input a first blood sample at a first predetermined time; a second procedure including prompting the patient to input second and third blood samples at second and third predetermined times, respectively; a third procedure including prompting the patient to input M blood samples at predetermined intervals beginning after a predetermined offset period; and a fourth procedure including prompting the patient to input N number of blood samples at N predetermined times of a day, respectively. The testing module selectively executes one or more of the structured tests.