The Procter & Gamble Company;The Cleveland Clinic Foundation
发明人:
Garcia-Garcia, Jose Carlos,Hazen, Stanley Leon,Wos, John August
申请号：
AU2016362298
公开号：
AU2016362298A1
申请日:
2016.12.01
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The invention provides a method of inhibiting the conversion of choline or carnitine to trimethylamine (TMA) and lowering TMAO in an individual comprising administering to the individual a composition comprising a compound set forth in FORMULA (I): FORMULA (I). The invention also provides for a method of inhibiting the production of TMA by bacteria comprising administering to the individual a composition comprising a compound set forth in FORMULA (I) wherein the compound is administered in an amount effective to inhibit formation of trimethylamine (TMA) from choline or carnitine in the individual.
