Robert A. Galemmo,Dean R. Artis,Xiaocong Michael Ye,Danielle Aubele,Anh Truong,Simeon Bowers,Roy K. Hom,Yong-Liang Zhu,R. Jeffrey Neitz,Jennifer Sealy,Marc Adler,Paul Beroza,John P. Anderson
申请号:
US12974401
公开号:
US08445503B2
申请日:
2010.12.21
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides compounds having a structure according to Formula (I):or a salt or solvate thereof, wherein ring A, X, R1, R2, R3, R4, R5 and R6 are defined herein. The invention further provides pharmaceutical compositions including the compounds of the invention and methods of making and using the compounds and compositions of the invention, e.g., in the treatment and prevention of various disorders, such as Parkinsons disease.