FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
发明人:
Stefan Barth,Theophilus Thepen,Manoel Barral-Netto,Aldina Barral,Johan Van Weyenbergh
申请号:
US15542549
公开号:
US20170369574A1
申请日:
2016.01.21
申请国别(地区):
US
年份:
2017
代理人:
摘要:
An immunotoxin for use in the treatment of leishmaniasis A wherein the immunotoxin comprises a portion which is specifically binding to the cellular surface receptor CD64 as a component A and a cell killing portion as a component B, wherein the cell killing portion alters the function, gene expression, or viability of a cell thereby killing Leishmania-infected macrophages and by this eliminates Leishmania.