The present invention provides a microfluidic channel structure for removing circulating tumor cells in blood, including: a blood sample inlet for blood samples to enter； a bead system retaining section having a first end and a second end, wherein the first end and blood Sample inlet connection； the bead blocking surface provided in the bead blocking section and adjacent to the second end, wherein the bead blocking section defines channels at each end of the bead blocking surface for the processed blood sample to circulate, and The bead blocking surface and the first end cause a plurality of beads to form a bead array in the bead system retaining section； and a blood sample outlet connected to the second end of the bead system retaining section.本創作提供一種用於移除血液中循環腫瘤細胞的微流道結構，包括：供血液樣本進入的血液樣本入口；具第一端及第二端的珠體繫留區段，其中第一端與血液樣本入口連接；設於珠體繫留區段中且鄰近第二端的珠體攔阻表面，其中珠體繫留區段在珠體攔阻表面的兩端各界定出通道，供經處理的血液樣本流通，且珠體攔阻表面與第一端使複數個珠體於珠體繫留區段中形成珠體陣列；以及與珠體繫留區段的第二端連接的血液樣本出口。
