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COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY
专利权人:
MEMORIAL SLOAN-KETTERING CANCER CENTER
发明人:
BRENTJENS, Renier, J.,PEGRAM, Hollie, J.
申请号:
PH12015501880
公开号:
PH12015501880A1
申请日:
2015.08.26
申请国别(地区):
PH
年份:
2016
代理人:
摘要:
The present invention provides for methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to immunoresponsive cells bearing antigen receptors, which can be chimeric antigen receptors (CARs), which express introduced ligands for immunomodulatory molecules. In particular embodiments, engineered immunoresponsive cells are antigen-directed and resist immunosuppression and/or have enhanced immune-activating properties.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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