The present invention provides a medicament having a wider treatment spectrum, causing a fewer side effects and superior in tolerability and safety, as compared to known typical antipsychotic agents and atypical antipsychotic agents. The present invention related to a medicament containing (I) a compound which is 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one or a salt thereof, and (II) at least one drug selected from the group consisting of a mood stabilizer, a serotonin reuptake inhibitor, a norepinephrine reuptake inhibitor, a serotonin and norepinephrine reuptake inhibitor, a noradrenergic and specific serotonergic antidepressant, an antianxiety drug, a tricyclic antidepressant, a tetracyclic antidepressant, an antipsychotic drug and an anti-ADHD drug, in combination.本發明提供一種與已知典型的抗精神病藥和非典型的抗精神病藥相比而具有更廣效的治療、引起較少的副作用及卓越的耐受性和安全性之藥物。本發明係關於一種含有下列者之組合的藥物：(I)化合物，其為7-〔4-(4-苯並〔b〕噻吩-4-基-哌-1-基)丁氧基〕-1H-喹啉-2-酮或其鹽，及(II)至少一種選自下列者之藥：情緒安定劑、血清素再吸收抑制劑、正腎上腺素再吸收抑制劑、血清素與正腎上腺素再吸收抑制劑、正腎上腺素與專一性血清素抗抑鬱藥、抗焦慮藥、三環抗抑鬱藥、四環抗抑鬱藥、抗精神病藥及抗-ADHD藥。
