Pharmaceutical composition comprising an inhibitor of proprotein Convertase subtilisin kexina - 9 (PCSK9)； and its use to reduce the levels of lipoprotein (a) (LP (a)).

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专利权人:

INC.;REGENERON PHARMACEUTICALS

发明人:

SWERGOD GARY

申请号：

CL2014000605

公开号：

CL2014000605A1

申请日:

2014.03.13

申请国别(地区):

CL

年份:

2014

代理人:

摘要：

The present invention provides methods for reducing lipoprotein(a) (Lp(a)) in patients. The methods of the present invention comprise selecting a patient who exhibits elevated serum Lp(a), and administering to the patient a pharmaceutical composition comprising a PCSK9 inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody such as the exemplary antibody referred to herein as mAb316P.Se describe el uso de una composición que comprende un inhibidor de proteína convertasa subtilisina/kexina de tipo 9 (PCSK9) para preparar un medicamento útil para reducir los niveles séricos de lipoproteína(a) (Lp(a)).

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/