There is provided herein a brachytherapy delivery system for the internal delivery and positioning of therapeutic agent, most particularly, a discrete radiation emitting particulate, within or in proximity to a vertebral or other bony tumor. The system comprises an elongated bone cannula having a proximal and a distal end, the distal end being suitable for disposition within bone. The bone cannula further comprises a bore disposed longitudinally therethrough suitable to axially and slidably receive an elongated and cannulated therapy delivery apparatus through which the therapeutic agent is delivered.