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PHARMACEUTICAL COMBINATIONS, INCLUDING ANTI-INFLAMMATORY AND ANTIOXIDANT CONJUGATES USED FOR TREATING METABOLISM DISORDERS
- 专利权人:
- ДЖЕНМЕДИКА ТЕРАПЬЮТИКС СЛ (ES)
- 发明人:
- СЕСАР КАСТРО ПАЛОМИНО ЛАРИА Хулио (ES),МАРТИ КЛАУСЕЛЬ Лук (ES),СОРСАНО ОЛАРТЕ Антонио (ES),ГАРСИЯ ВИСЕНТЕ Сильвия (ES),МИАН Алек (ES)
- 申请号：
- RU2014114932/15
- 公开号：
- RU2014114932A
- 申请日:
- 2012.09.14
- 申请国别(地区):
- RU
- 年份:
- 2015
- 代理人:
- 摘要：
- 1. A pharmaceutical combination comprising: (a) an anti-inflammatory / antioxidant conjugate； and (b) an insulin secretion promoter, an insulin sensitizer, an alpha glucosidase inhibitor, a peptide analog, or a combination thereof. 2. The pharmaceutical combination of claim 1, wherein the anti-inflammatory / antioxidant conjugate is selected from (R) -2-acetamido-3- (2-hydroxybenzoylthio) propionic acid； (R) -methyl 2-acetamido-3- (2-hydroxybenzoylthio) propanoate； (R) -ethyl 2-acetamido-3- (2-hydroxybenzoylthio) propanoate； (R) -2-acetamido-3- (2-acetoxybenzoylthio) propionic acid； (R) -methyl 2-acetamido-3- ( 2-acetoxybenzoylthio) propanoate； (R) -ethyl 2-acetamido-3- (2-acetoxybenzoylthio) propanoate； (R) -2-acetamido-3- (2-hydroxy-4- (trifluoromethyl) benzoylthio) propionic acid； ( R) -methyl 2-acetamido-3- (2-hydr hydroxy-4- (trifluoromethyl) benzoylthio) propanoate； (R) -ethyl 2-acetamido-3- (2-hydroxy-4- (trifluoromethyl) benzoylthio) propanoate； (R) -2-acetamido-3- (2-acetoxy -4- (trifluoromethyl) benzoylthio) propanoic acid； (R) -methyl 2-acetamido-3- (2-acetoxy-4- (trifluoromethyl) benzoylthio) propanoate； (R) -ethyl 2-acetamido-3- (2- acetoxy-4- (trifluoromethyl) benzoylthio) propanoate； (R) -2-acetamido-3- (2-acetoxy-4- (trifluoromethyl) benzoylthio) propionic acid； (R) -methyl 2-acetamido-3- (2- acetoxy-4- (trifluoromethyl) benzoylthio) propanoate； (R) -ethyl 2-acetamido-3- (2-acetoxy-4- (trifluoromethyl) benzoylthio) propanoate； (R) -2-acetam do-3- (2 ', 4'-difluoro-4-hydroxybiphenylcarbonylthio) propionic acid (GMC-252)； (R) -methyl 2-acetamido-3- (2', 4'-difluoro-4-hydroxybiphenylcarbonylthio) propanoate ； (R) -ethyl 2-acetamido-3- (2 ', 4'-difluoro-4-hydroxybiphenylcarbonylthio) propanoate； (R) -2-acetamido-3- (4-acetoxy-2', 4'-difluorobiphenylcarbonylthio) propionic acid； (R) -methyl 2-ace1. Фармацевтическая комбинация, содержащая:(a) конъюгат противовоспалительное средство/антиоксидантное средство； и(b) стимулятор секреции инсулина, сенсибилизатор
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
