JONCKERS, TIM HUGO MARIA,RABOISSON, PIERRE JEAN-MARIE BERNARD,VANDYCK, KOEN,VAN HOOF, STEVEN MAURICE PAULA,HU, LILI,TAHRI, ABDELLAH
申请号：
PL10718207
公开号：
PL2430035T3
申请日:
2010.05.11
申请国别(地区):
PL
年份:
2013
代理人:
摘要：
Compounds of the formula I: including any possible stereoisomers thereof, wherein: R 4 is a monophosphate, diphosphate or triphosphate ester； or R 4 is R 7 is optionally substituted phenyl, optionally substituted naphthyl, or optionally substituted indolyl； R 8 and R 8' are hydrogen, C 1 -C 6 alkyl, benzyl, or phenyl； or R 8 and R 8' form C 3 -C 7 cycloalkyl； R 9 is C 1 -C 10 alkyl, C 3 -C 7 cycloalkyl, phenyl or phenyl-C 1 -C 6 alkyl, wherein the phenyl moiety in phenyl or phenyl-C 1 -C 6 alkyl is optionally substituted； or a pharmaceutically acceptable salt or solvate thereof； pharmaceutical formulations and the use of compounds I as HCV inhibitors.
