PROBLEM TO BE SOLVED: To provide a medical drug, a quasi drug or a food product useful for improving the stiffness of a joint such as a knee joint, or material or a drug product that can be blended in the medical drug, the quasi drug or the food product.SOLUTION: In a first embodiment, a joint stiffness improving agent is provided that contains a milk-fat globule membrane as an active ingredient. In a second embodiment, a joint stiffness improving agent is provided that is identical to the joint stiffness improving agent in the first embodiment except that the milk fat globule membrane contains a phospholipid of 5-100 mass%, or sphingomyelin of 1-50 mass%. In a third embodiment, a joint stiffness improving agent is provided that is identical to the joint stiffness improving agent in the first or the second embodiment except that the dosage form of the joint stiffness improving agent is a solid formulation for oral administration such as a tablet.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】膝関節等の関節のこわばりの改善に有用な医薬品、医薬部外品又は食品、或いはこれらに配合可能な素材又は製剤の提供。【解決手段】乳脂肪球皮膜を有効成分とする関節のこわばり改善剤。乳脂肪球皮膜が、リン脂質を5~100質量%、あるいはスフィンゴミエリンを1~50質量%含有する、前記関節のこわばり改善剤。剤型が、錠剤等経口投与用の固形製剤である、前記関節のこわばり改善剤。【選択図】なし
